Analysis of Dominant HIV Quasispecies Suggests Independent Viral Evolution Within Spinal Granulomas Coinfected with Mycobacterium tuberculosis and HIV-1 Subtype C

Extrapulmonary tuberculosis (TB) is a significant public health challenge in South Africa and worldwide, largely fuelled by the HIV epidemic. In spinal TB, Mycobacteria infect the spinal column without dissemination to the spinal cord. The immune microenvironment, target cell characteristics, and ot...

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Vydáno v:AIDS Res Hum Retroviruses
Hlavní autoři: Danaviah, Sivapragashini, de Oliveira, Tulio, Gordon, Michelle, Govender, Shunmugam, Chelule, Paul, Pillay, Sureshnee, Naicker, Thajasvarie, Cassol, Sharon, Ndung'u, Thumbi
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2016
Témata:
Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125288/
https://ncbi.nlm.nih.gov/pubmed/26564424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0189
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