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Impaired function of trophoblast cells derived from translocated hESCs may explain pregnancy loss in women with balanced translocation (11;22)
PURPOSE: The aim of the study was to study whether the trophoblasts carrying unbalanced translocation 11,22 [t(11;12)] display abnormal expression of trophoblastic genes and impaired functional properties that may explain implantation failure. METHODS: t(11;22) hESCs and control hESCs were different...
Guardado en:
| Publicado en: | J Assist Reprod Genet |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer US
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125145/ https://ncbi.nlm.nih.gov/pubmed/27503403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0781-6 |
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