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Impaired function of trophoblast cells derived from translocated hESCs may explain pregnancy loss in women with balanced translocation (11;22)

PURPOSE: The aim of the study was to study whether the trophoblasts carrying unbalanced translocation 11,22 [t(11;12)] display abnormal expression of trophoblastic genes and impaired functional properties that may explain implantation failure. METHODS: t(11;22) hESCs and control hESCs were different...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Shpiz, Alina, Ben-Yosef, Dalit, Kalma, Yael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125145/
https://ncbi.nlm.nih.gov/pubmed/27503403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0781-6
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