GWAS study using DNA pooling strategy identifies association of variant rs4910623 in OR52B4 gene with anti-VEGF treatment response in age-related macular degeneration

Pooled DNA based GWAS to determine genetic association of SNPs with visual acuity (VA) outcome in anti-vascular endothelial growth factor (anti-VEGF) treated neovascular age-related macular degeneration (nAMD) patients. We performed pooled DNA based GWAS on 285 anti-VEGF treated nAMD patients using...

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Publicat a:Sci Rep
Autors principals: Riaz, Moeen, Lorés-Motta, Laura, Richardson, Andrea J., Lu, Yi, Montgomery, Grant, Omar, Amer, Koenekoop, Robert K., Chen, John, Muether, Philipp, Altay, Lebriz, Schick, Tina, Fauser, Sascha, Smailhodzic, Dzenita, van Asten, Freekje, de Jong, Eiko K., Hoyng, Carel B., Burdon, Kathryn P., MacGregor, Stuart, Guymer, Robyn H., den Hollander, Anneke I., Baird, Paul N.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124940/
https://ncbi.nlm.nih.gov/pubmed/27892514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37924
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