A genetic variant in NRP1 is associated with worse response to ranibizumab treatment in neovascular age-related macular degeneration

OBJECTIVE: The aim of the study was to investigate the role of single-nucleotide polymorphisms (SNPs) located in the neuropilin-1 (NRP1) gene in treatment response to antivascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (nvAMD). METHODS: Four SNPs in...

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Bibliographic Details
Published in:Pharmacogenet Genomics
Main Authors: Lorés-Motta, Laura, van Asten, Freekje, Muether, Philipp S., Smailhodzic, Dzenita, Groenewoud, Joannes M., Omar, Amer, Chen, John, Koenekoop, Robert K., Fauser, Sascha, Hoyng, Carel B., den Hollander, Anneke I., de Jong, Eiko K.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890827/
https://ncbi.nlm.nih.gov/pubmed/26426212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000180
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