A genetic variant in NRP1 is associated with worse response to ranibizumab treatment in neovascular age-related macular degeneration

OBJECTIVE: The aim of the study was to investigate the role of single-nucleotide polymorphisms (SNPs) located in the neuropilin-1 (NRP1) gene in treatment response to antivascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (nvAMD). METHODS: Four SNPs in...

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Détails bibliographiques
Publié dans:Pharmacogenet Genomics
Auteurs principaux: Lorés-Motta, Laura, van Asten, Freekje, Muether, Philipp S., Smailhodzic, Dzenita, Groenewoud, Joannes M., Omar, Amer, Chen, John, Koenekoop, Robert K., Fauser, Sascha, Hoyng, Carel B., den Hollander, Anneke I., de Jong, Eiko K.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2016
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890827/
https://ncbi.nlm.nih.gov/pubmed/26426212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000180
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