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Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats

Brain ischemic preconditioning (PC) provides vital insights into the endogenous protection against stroke. Genomic and epigenetic responses to PC condition the brain into a state of ischemic tolerance. Notably, PC induces the elevation of histone acetylation, consistent with evidence that histone de...

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Publicado en:Front Mol Neurosci
Autores principales: Yang, Xiaoyu, Wu, Qimei, Zhang, Lei, Feng, Linyin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124709/
https://ncbi.nlm.nih.gov/pubmed/27965534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00131
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