Reassessing the Role of the Active TGF-β1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations

Objective. To determine active TGF-β1 (aTGF-β1) levels in serum, skin, and peripheral blood mononuclear cell (PBMC) culture supernatants and to understand their associations with clinical parameters in systemic sclerosis (SSc) patients. Methods. We evaluated serum samples from 56 SSc patients and 24...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dis Markers
Auteurs principaux: Dantas, Andréa Tavares, Gonçalves, Sayonara Maria Calado, de Almeida, Anderson Rodrigues, Gonçalves, Rafaela Silva Guimarães, Sampaio, Maria Clara Pinheiro Duarte, Vilar, Kamila de Melo, Pereira, Michelly Cristiny, Rêgo, Moacyr Jesus Barreto de Melo, Pitta, Ivan da Rocha, Marques, Claudia Diniz Lopes, Duarte, Angela Luzia Branco Pinto, Pitta, Maira Galdino da Rocha
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124685/
https://ncbi.nlm.nih.gov/pubmed/27965520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6064830
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