Synthesis of a Novel Thiazolidinedione and Evaluation of Its Modulatory Effect on IFN-γ, IL-6, IL-17A, and IL-22 Production in PBMCs from Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is an autoimmune disease frequently characterized by chronic synovitis of multiple joints. The pathogenesis of RA is complex and involves many proinflammatory cytokines as Th17 related ones. PPARγ is a nuclear receptor activator that represses proinflammatory gene expressio...

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Main Authors: da Rocha Junior, Laurindo Ferreira, de Melo Rêgo, Moacyr Jesus Barreto, Cavalcanti, Mariana Brayner, Pereira, Michelly Cristiny, Pitta, Marina Galdino da Rocha, de Oliveira, Priscilla Stela Santana, Gonçalves, Sayonara Maria Calado, Duarte, Angela Luzia Branco Pinto, de Lima, Maria do Carmo Alves, Pitta, Ivan da Rocha, Pitta, Maira Galdino da Rocha
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773918/
https://ncbi.nlm.nih.gov/pubmed/24078927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/926060
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