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Multi-locus Test and Correction for Confounding Effects in Genome-Wide Association Studies

Genome-wide association studies (GWAS) examine a large number of genetic variants, e.g., single nucleotide polymorphisms (SNP), and associate them with a disease of interest. Traditional statistical methods for GWASs can produce spurious associations, due to limited information from individual SNPs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biostat
Hauptverfasser: Chen, Donglai, Liu, Chuanhai, Xie, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124542/
https://ncbi.nlm.nih.gov/pubmed/27232635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/ijb-2015-0091
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