Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.

Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In prokaryotes, noncovalent DNA-ditercalinium complexes are incorrectly recognized by the uvrABC repair system as covalent lesions on DNA. In eukaryotes, mitochondrial DNA is degra...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gao, Q, Williams, L D, Egli, M, Rabinovich, D, Chen, S L, Quigley, G J, Rich, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2006181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2422
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