Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.

Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In prokaryotes, noncovalent DNA-ditercalinium complexes are incorrectly recognized by the uvrABC repair system as covalent lesions on DNA. In eukaryotes, mitochondrial DNA is degra...

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Detalhes bibliográficos
Main Authors: Gao, Q, Williams, L D, Egli, M, Rabinovich, D, Chen, S L, Quigley, G J, Rich, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51244/
https://ncbi.nlm.nih.gov/pubmed/2006181
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