Exogenous Secreted Frizzled-Related Protein-4 Modulates Steroidogenesis of Rat Granulosa Cells through Wnt/β-catenin and PI3K/AKT Signaling Pathways

BACKGROUND: It has been reported that secreted frizzled-related protein-4 known as an antagonist of Wnt signaling pathway plays a role in luteinization process of rodent granulosa cells. The purpose of this study was twofold: 1) to determine whether recombinant human secreted frizzled-related protei...

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Bibliografske podrobnosti
izdano v:Avicenna J Med Biotechnol
Main Authors: Hossein, Ghamartaj, Khanmohammadi, Manijeh, Sahranavard Fard, Parisa, Heidarian, Yasaman, Kazemnejad, Somaieh, Akhondi, Mohammad Mehdi
Format: Artigo
Jezik:Inglês
Izdano: Avicenna Research Institute 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124252/
https://ncbi.nlm.nih.gov/pubmed/27920883
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