Adenosine A(2A) receptor and ecto-5′-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE)

Refractoriness to existing medications of up to 80 % of the patients with mesial temporal lobe epilepsy (MTLE) prompts for finding new antiepileptic drug targets. The adenosine A(2A) receptor emerges as an interesting pharmacological target since its excitatory nature partially counteracts the domin...

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Dettagli Bibliografici
Pubblicato in:Purinergic Signal
Autori principali: Barros-Barbosa, Aurora R., Ferreirinha, Fátima, Oliveira, Ângela, Mendes, Marina, Lobo, M. Graça, Santos, Agostinho, Rangel, Rui, Pelletier, Julie, Sévigny, Jean, Cordeiro, J. Miguel, Correia-de-Sá, Paulo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124012/
https://ncbi.nlm.nih.gov/pubmed/27650530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9535-2
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