Adenosine A(2A) receptor and ecto-5′-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE)

Refractoriness to existing medications of up to 80 % of the patients with mesial temporal lobe epilepsy (MTLE) prompts for finding new antiepileptic drug targets. The adenosine A(2A) receptor emerges as an interesting pharmacological target since its excitatory nature partially counteracts the domin...

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Publicat a:Purinergic Signal
Autors principals: Barros-Barbosa, Aurora R., Ferreirinha, Fátima, Oliveira, Ângela, Mendes, Marina, Lobo, M. Graça, Santos, Agostinho, Rangel, Rui, Pelletier, Julie, Sévigny, Jean, Cordeiro, J. Miguel, Correia-de-Sá, Paulo
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124012/
https://ncbi.nlm.nih.gov/pubmed/27650530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9535-2
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