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CD39 overexpression does not attenuate renal fibrosis in the unilateral ureteric obstructive model of chronic kidney disease

Chronic kidney disease has multiple etiologies, but its single, hallmark lesion is renal fibrosis. CD39 is a key purinergic enzyme in the hydrolysis of ATP and increased CD39 activity on regulatory T cells (Treg) is protective in adriamycin-induced renal fibrosis. We examined the effect of overexpre...

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Publicat a:Purinergic Signal
Autors principals: Roberts, Veena, Lu, B., Chia, J., Cowan, P.J., Dwyer, K.M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124005/
https://ncbi.nlm.nih.gov/pubmed/27565966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9528-1
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