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Morphine enhances IL-1β release through toll-like receptor 4-mediated endocytic pathway in microglia
Morphine creates a neuroinflammatory response and enhances release of the proinflammatory cytokines like interleukin-1β (IL-1β), which compromises morphine analgesia as well as induces morphine tolerance. In this study, we attempted to investigate the mechanisms of morphine induced IL-1β synthesis a...
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| Publicat a: | Purinergic Signal |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Netherlands
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124002/ https://ncbi.nlm.nih.gov/pubmed/27506813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9525-4 |
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