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Role for the IFT-A complex in selective transport to the primary cilium

Intraflagellar transport sub-complex A (IFT-A) is known to regulate retrograde IFT in the cilium. To rigorously assess its other possible roles, we knocked out an IFT-A subunit, IFT121/WDR35, in mammalian cells and screened the localization of more than 50 proteins. We found that Wdr35 regulates cil...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Fu, Wenxiang, Wang, Lei, Kim, Sehyun, Li, Ji, Dynlacht, Brian David
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123888/
https://ncbi.nlm.nih.gov/pubmed/27806291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.018
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