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Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81

Intraflagellar transport (IFT) of ciliary precursors such as tubulin from the cytoplasm to the ciliary tip is involved in the construction of the cilium, a hairlike organelle found on most eukaryotic cells. However, the molecular mechanisms of IFT are poorly understood. Here, we found that the two c...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bhogaraju, Sagar, Cajanek, Lukas, Fort, Cécile, Blisnick, Thierry, Weber, Kristina, Taschner, Michael, Mizuno, Naoko, Lamla, Stefan, Bastin, Philippe, Nigg, Erich A., Lorentzen, Esben
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359902/
https://ncbi.nlm.nih.gov/pubmed/23990561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240985
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