Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81

Intraflagellar transport (IFT) of ciliary precursors such as tubulin from the cytoplasm to the ciliary tip is involved in the construction of the cilium, a hairlike organelle found on most eukaryotic cells. However, the molecular mechanisms of IFT are poorly understood. Here, we found that the two c...

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Publicat a:Science
Autors principals: Bhogaraju, Sagar, Cajanek, Lukas, Fort, Cécile, Blisnick, Thierry, Weber, Kristina, Taschner, Michael, Mizuno, Naoko, Lamla, Stefan, Bastin, Philippe, Nigg, Erich A., Lorentzen, Esben
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359902/
https://ncbi.nlm.nih.gov/pubmed/23990561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240985
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