N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

The RNA modification N6-methyladenosine (m(6)A) post-transcriptionally regulates RNA function. The cellular machinery that controls m(6)A includes methyltransferases and demethylases that add or remove this modification, as well as m(6)A-binding YTHDF proteins that promote the translation or degrada...

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Publicat a:Cell Host Microbe
Autors principals: Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123813/
https://ncbi.nlm.nih.gov/pubmed/27773535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.09.015
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