N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

The RNA modification N6-methyladenosine (m(6)A) post-transcriptionally regulates RNA function. The cellular machinery that controls m(6)A includes methyltransferases and demethylases that add or remove this modification, as well as m(6)A-binding YTHDF proteins that promote the translation or degrada...

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Pubblicato in:Cell Host Microbe
Autori principali: Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123813/
https://ncbi.nlm.nih.gov/pubmed/27773535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.09.015
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