Killer immunoglobulin-like receptor (KIR) and KIR–ligand genotype do not correlate with clinical outcome of renal cell carcinoma patients receiving high-dose IL2

NK cells play a role in many cancer immunotherapies. NK cell activity is tightly regulated by killer immunoglobulin-like receptor (KIR) and KIR–ligand interactions. Inhibitory KIR–ligands have been identified as HLA molecules, while activating KIR–ligands are largely unknown. Individuals that have n...

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Bibliografische gegevens
Gepubliceerd in:Cancer Immunol Immunother
Hoofdauteurs: Wang, Wei, Erbe, Amy K., Gallenberger, Mikayla, Kim, KyungMann, Carmichael, Lakeesha, Hess, Dustin, Mendonca, Eneida A., Song, Yiqiang, Hank, Jacquelyn A., Cheng, Su-Chun, Signoretti, Sabina, Atkins, Michael, Carlson, Alexander, Weiss, Jonathan M., Mier, James, Panka, David, McDermott, David F., Sondel, Paul M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123674/
https://ncbi.nlm.nih.gov/pubmed/27695964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1904-8
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