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Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data

BACKGROUND: Transcriptional regulation of gene expression is essential for cellular differentiation and function, and defects in the process are associated with cancer. The ENCODE project has mapped potential regulatory sites across the complete genome in many cell types, and these regions have been...

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Pubblicato in:Mol Cancer
Autori principali: Shar, Nisar A., Vijayabaskar, M. S., Westhead, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123355/
https://ncbi.nlm.nih.gov/pubmed/27887606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0560-0
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