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Recurrent Somatic Mutations in Regulatory Regions of Human Cancer Genomes
Aberrant regulation of gene expression in cancer can promote survival and proliferation of cancer cells. Here we integrate TCGA whole genome sequencing data of 436 patients from eight cancer subtypes with ENCODE and other regulatory annotations to identify point mutations in regulatory regions. We f...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485503/ https://ncbi.nlm.nih.gov/pubmed/26053494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3332 |
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