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Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader–Willi syndrome
OBJECTIVE: Extreme obesity is a core phenotypic feature of Prader–Willi syndrome (PWS). Among numerous metabolic regulators, the endocannabinoid (eCB) system is critically involved in controlling feeding, body weight, and energy metabolism, and a globally acting cannabinoid-1 receptor (CB(1)R) block...
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| Publicado no: | Mol Metab |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123200/ https://ncbi.nlm.nih.gov/pubmed/27900261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.10.004 |
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