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The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
Vascular permeability and neovascularization are implicated in many diseases including retinopathies and diabetic wound healing. Robo4 is an endothelial-specific transmembrane receptor that stabilizes the vasculature, as shown in Robo4(−/−) mice that develop hyperpermeability, but how Robo4 signals...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123080/ https://ncbi.nlm.nih.gov/pubmed/27882935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13517 |
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