Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain

Cotranslational chaperones assist in de novo folding of nascent polypeptides in all organisms. In yeast, the heterodimeric ribosome-associated complex (RAC) forms a unique chaperone triad with the Hsp70 homologue Ssb. We report the X-ray structure of full length Ssb in the ATP-bound open conformatio...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gumiero, Andrea, Conz, Charlotte, Gesé, Genís Valentín, Zhang, Ying, Weyer, Felix Alexander, Lapouge, Karine, Kappes, Julia, von Plehwe, Ulrike, Schermann, Géza, Fitzke, Edith, Wölfle, Tina, Fischer, Tamás, Rospert, Sabine, Sinning, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123055/
https://ncbi.nlm.nih.gov/pubmed/27882919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13563
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