Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger

IMPORTANCE: Young febrile infants are at substantial risk of serious bacterial infections; however, the current culture-based diagnosis has limitations. Analysis of host expression patterns (“RNA biosignatures”) in response to infections may provide an alternative diagnostic approach. OBJECTIVE: To...

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Publicat a:JAMA
Autors principals: Mahajan, Prashant, Kuppermann, Nathan, Mejias, Asuncion, Suarez, Nicolas, Chaussabel, Damien, Casper, T. Charles, Smith, Bennett, Alpern, Elizabeth R., Anders, Jennifer, Atabaki, Shireen M., Bennett, Jonathan E., Blumberg, Stephen, Bonsu, Bema, Borgialli, Dominic, Brayer, Anne, Browne, Lorin, Cohen, Daniel M., Crain, Ellen F., Cruz, Andrea T., Dayan, Peter S., Gattu, Rajender, Greenberg, Richard, Hoyle, John D., Jaffe, David M., Levine, Deborah A., Lillis, Kathleen, Linakis, James G., Muenzer, Jared, Nigrovic, Lise E., Powell, Elizabeth C., Rogers, Alexander J., Roosevelt, Genie, Ruddy, Richard M., Saunders, Mary, Tunik, Michael G., Tzimenatos, Leah, Vitale, Melissa, Dean, J. Michael, Ramilo, Octavio
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122927/
https://ncbi.nlm.nih.gov/pubmed/27552618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.9207
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