Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger

IMPORTANCE: Young febrile infants are at substantial risk of serious bacterial infections; however, the current culture-based diagnosis has limitations. Analysis of host expression patterns (“RNA biosignatures”) in response to infections may provide an alternative diagnostic approach. OBJECTIVE: To...

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Publicado no:JAMA
Main Authors: Mahajan, Prashant, Kuppermann, Nathan, Mejias, Asuncion, Suarez, Nicolas, Chaussabel, Damien, Casper, T. Charles, Smith, Bennett, Alpern, Elizabeth R., Anders, Jennifer, Atabaki, Shireen M., Bennett, Jonathan E., Blumberg, Stephen, Bonsu, Bema, Borgialli, Dominic, Brayer, Anne, Browne, Lorin, Cohen, Daniel M., Crain, Ellen F., Cruz, Andrea T., Dayan, Peter S., Gattu, Rajender, Greenberg, Richard, Hoyle, John D., Jaffe, David M., Levine, Deborah A., Lillis, Kathleen, Linakis, James G., Muenzer, Jared, Nigrovic, Lise E., Powell, Elizabeth C., Rogers, Alexander J., Roosevelt, Genie, Ruddy, Richard M., Saunders, Mary, Tunik, Michael G., Tzimenatos, Leah, Vitale, Melissa, Dean, J. Michael, Ramilo, Octavio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122927/
https://ncbi.nlm.nih.gov/pubmed/27552618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.9207
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