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Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin

Ricin is a type II ribosome-inactivating protein (RIP) that depurinates A(4324) at the sarcin-ricin loop of 28 S ribosomal RNA (rRNA), thus inactivating the ribosome by preventing elongation factors from binding to the GTPase activation centre. Recent studies have disclosed that the conserved C-term...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fan, Xiaojiao, Zhu, Yuwei, Wang, Chongyuan, Niu, Liwen, Teng, Maikun, Li, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122897/
https://ncbi.nlm.nih.gov/pubmed/27886256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37803
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