Solution structure of human P1•P2 heterodimer provides insights into the role of eukaryotic stalk in recruiting the ribosome-inactivating protein trichosanthin to the ribosome

Lateral ribosomal stalk is responsible for binding and recruiting translation factors during protein synthesis. The eukaryotic stalk consists of one P0 protein with two copies of P1•P2 heterodimers to form a P0(P1•P2)(2) pentameric P-complex. Here, we have solved the structure of full-length P1•P2 b...

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Hlavní autoři: Lee, Ka-Ming, Yusa, Kazuyuki, Chu, Lai-On, Yu, Conny Wing-Heng, Oono, Moe, Miyoshi, Tomohiro, Ito, Kosuke, Shaw, Pang-Chui, Wong, Kam-Bo, Uchiumi, Toshio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794596/
https://ncbi.nlm.nih.gov/pubmed/23892290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt636
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