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Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway

17β-estradiol (E2), the primary circulating estrogen hormone, mediates physiological and pathophysiological functions of breast tissue mainly through estrogen receptor α (ERα). Upon binding to E2, ERα modulates the expression of target genes involved in the regulation of cellular proliferation prima...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Yaşar, Pelin, Ayaz, Gamze, Muyan, Mesut
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122896/
https://ncbi.nlm.nih.gov/pubmed/27886276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37808
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