Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

Estrogen receptor α (ERα), as a ligand-dependent transcription factor, mediates 17β-estradiol (E2) effects. ERα is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino- and carboxyl-termini. The interaction of the E2-activated ERα dim...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Muyan, Mesut, Güpür, Gizem, Yaşar, Pelin, Ayaz, Gamze, User, Sırma Damla, Kazan, Hasan Hüseyin, Huang, Yanfang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546503/
https://ncbi.nlm.nih.gov/pubmed/26295471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136423
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