Novel Antibody for the Treatment of Transthyretin Amyloidosis

Familial amyloidotic polyneuropathy (FAP) is a systemic amyloidosis mainly caused by amyloidogenic transthyretin (ATTR). This incurable disease causes death ∼10 years after onset. Although it has been widely accepted that conformational change of the monomeric form of transthyretin (TTR) is very imp...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hosoi, Akihiko, Su, Yu, Torikai, Masaharu, Jono, Hirofumi, Ishikawa, Daisuke, Soejima, Kenji, Higuchi, Hirofumi, Guo, Jianying, Ueda, Mitsuharu, Suenaga, Genki, Motokawa, Hiroaki, Ikeda, Tokunori, Senju, Satoru, Nakashima, Toshihiro, Ando, Yukio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122777/
https://ncbi.nlm.nih.gov/pubmed/27758856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738138
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