Novel Antibody for the Treatment of Transthyretin Amyloidosis

Familial amyloidotic polyneuropathy (FAP) is a systemic amyloidosis mainly caused by amyloidogenic transthyretin (ATTR). This incurable disease causes death ∼10 years after onset. Although it has been widely accepted that conformational change of the monomeric form of transthyretin (TTR) is very imp...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Hosoi, Akihiko, Su, Yu, Torikai, Masaharu, Jono, Hirofumi, Ishikawa, Daisuke, Soejima, Kenji, Higuchi, Hirofumi, Guo, Jianying, Ueda, Mitsuharu, Suenaga, Genki, Motokawa, Hiroaki, Ikeda, Tokunori, Senju, Satoru, Nakashima, Toshihiro, Ando, Yukio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Neurobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122777/
https://ncbi.nlm.nih.gov/pubmed/27758856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738138
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