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Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation

Aberrant cellular accumulation of cholesterol is associated with neuronal lysosomal storage disorders such as Niemann-Pick disease Type C (NPC). We have shown previously that l-norephedrine (l-Nor), a sympathomimetic amine, induces necrotic cell death associated with massive cytoplasmic vacuolation...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Funakoshi, Takeshi, Aki, Toshihiko, Tajiri, Masateru, Unuma, Kana, Uemura, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122773/
https://ncbi.nlm.nih.gov/pubmed/27756839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727404
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