Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism

Lamprey angiotensinogen (l-ANT) is a hormone carrier in the regulation of blood pressure, but it is also a heparin-dependent thrombin inhibitor in lamprey blood coagulation system. The detailed mechanisms on how angiotensin is carried by l-ANT and how heparin binds l-ANT and mediates thrombin inhibi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wei, Hudie, Cai, Haiyan, Wu, Jiawei, Wei, Zhenquan, Zhang, Fei, Huang, Xin, Ma, Lina, Feng, Lingling, Zhang, Ruoxi, Wang, Yunjie, Ragg, Hermann, Zheng, Ying, Zhou, Aiwu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122762/
https://ncbi.nlm.nih.gov/pubmed/27681598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.725895
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