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Tyrosine Kinase Signaling in Clear Cell and Papillary Renal Cell Carcinoma Revealed by Mass Spectrometry-Based Phosphotyrosine Proteomics

PURPOSE: Targeted therapies in renal cell carcinoma (RCC) are limited by acquired resistance. Novel therapeutic targets are needed to combat resistance and, ideally, target the unique biology of RCC subtypes. EXPERIMENTAL DESIGN: Tyrosine kinases provide critical oncogenic signaling and their inhibi...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Haake, Scott M., Li, Jiannong, Bai, Yun, Kinose, Fumi, Fang, Bin, Welsh, Eric, Zent, Roy, Dhillon, Jasreman, Pow-Sang, Julio, Chen, Yian Ann, Koomen, John, Rathmell, W. Kimryn, Fishman, Mayer, Haura, Eric B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122466/
https://ncbi.nlm.nih.gov/pubmed/27220961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1673
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