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Cabazitaxel operates anti-metastatic and cytotoxic via apoptosis induction and stalls brain tumor angiogenesis

Taxanes target microtubules and are clinically established chemotherapeutic agents with proven efficacy in human cancers. Cabazitaxel (XRP-6258, Jevtana®) is a second generation semisynthetic taxane with high chemotherapeutic potential in prostate cancer. There, cabazitaxel can overcome docetaxel-re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ghoochani, Ali, Majernik, Gökce Hatipoglu, Sehm, Tina, Wach, Sven, Buchfelder, Michael, Taubert, Helge, Eyupoglu, Ilker Y., Savaskan, Nicolai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122391/
https://ncbi.nlm.nih.gov/pubmed/27203678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9439
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