A novel p70 S6 kinase-microRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression

Ovarian cancer is the leading cause of death of all gynecologic tumors, associated with widespread peritoneal dissemination and malignant ascites. Key to this is the ability to form multicellular spheroids (MCS); however, the tumor-specific factors that regulate MCS formation are unclear. p70 S6 kin...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lam, Sophia So Ngo, Ip, Carman Ka Man, Mak, Abby Sin Chi, Wong, Alice Sze Tsai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122372/
https://ncbi.nlm.nih.gov/pubmed/27191261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9345
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