Immortalization capacity of HPV types is inversely related to chromosomal instability

High-risk human papillomavirus (hrHPV) types induce immortalization of primary human epithelial cells. Previously we demonstrated that immortalization of human foreskin keratinocytes (HFKs) is HPV type dependent, as reflected by the presence or absence of a crisis period before reaching immortality....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schütze, Denise M., Krijgsman, Oscar, Snijders, Peter J.F., Ylstra, Bauke, Weischenfeldt, Joachim, Mardin, Balca R., Stütz, Adrian M., Korbel, Jan O., de Winter, Johan P., Meijer, Chris J.L.M., Quint, Wim G.V., Bosch, Leontien, Wilting, Saskia M., Steenbergen, Renske D.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122336/
https://ncbi.nlm.nih.gov/pubmed/26993771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8058
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