The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons

Transforming growth factor β (TGFβ)-mediated anti-proliferative and differentiating effects promote neuronal differentiation during embryonic central nervous system development. TGFβ downstream signals, composed of activated SMAD2/3, SMAD4 and a FOXO family member, promote the expression of cyclin-d...

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Опубликовано в: :Oncotarget
Главные авторы: Vezzali, Riccardo, Weise, Stefan Christopher, Hellbach, Nicole, Machado, Venissa, Heidrich, Stefanie, Vogel, Tanja
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper: Gerotarget (Focus on Aging)
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122323/
https://ncbi.nlm.nih.gov/pubmed/27224923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9545
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