GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells

Post-transcriptional gene silencing holds great promise in discovery research for addressing intricate biological questions and as therapeutics. While various gene silencing approaches, such as siRNA and CRISPR-Cas9 techniques, are available, these cannot be effectively applied to “hard-to-transfect...

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發表在:Sci Rep
Main Authors: Fazil, Mobashar Hussain Urf Turabe, Ong, Seow Theng, Chalasani, Madhavi Latha Somaraju, Low, Jian Hui, Kizhakeyil, Atish, Mamidi, Akshay, Lim, Carey Fang Hui, Wright, Graham D., Lakshminarayanan, Rajamani, Kelleher, Dermot, Verma, Navin Kumar
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121623/
https://ncbi.nlm.nih.gov/pubmed/27883055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37721
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