GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells

Post-transcriptional gene silencing holds great promise in discovery research for addressing intricate biological questions and as therapeutics. While various gene silencing approaches, such as siRNA and CRISPR-Cas9 techniques, are available, these cannot be effectively applied to “hard-to-transfect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fazil, Mobashar Hussain Urf Turabe, Ong, Seow Theng, Chalasani, Madhavi Latha Somaraju, Low, Jian Hui, Kizhakeyil, Atish, Mamidi, Akshay, Lim, Carey Fang Hui, Wright, Graham D., Lakshminarayanan, Rajamani, Kelleher, Dermot, Verma, Navin Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121623/
https://ncbi.nlm.nih.gov/pubmed/27883055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37721
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