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The Bull-James Assembly as a Chiral Auxiliary and Shift Reagent in Kinetic Resolution of Alkyne Amines by the CuAAC Reaction()

The Bull-James boronic acid assembly is used simultaneously as a chiral auxilary for kinetic resolution and as a chiral shift reagent for in situ enantiomeric excess (ee) determination by (1)H NMR spectroscopy. Chiral terminal alkyne-containing amines, and their corresponding chiral triazoles formed...

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Foilsithe in:Org Biomol Chem
Main Authors: Brittain, William D. G., Chapin, Brette M., Zhai, Wenlei, Lynch, Vincent M., Buckley, Benjamin R., Anslyn, Eric V., Fossey, John S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121074/
https://ncbi.nlm.nih.gov/pubmed/27604036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01623e
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