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Crystal Structures of the CO- and NO-Bound DosS GAF-A Domain and Implications for DosS Signaling in Mycobacterium tuberculosis
DosS is a sensor in Mycobacterium tuberculosis that differentially responds to O(2), NO, and CO, as well as to changes in the redox state of the prosthetic heme iron atom. The ferrous protein and its Fe(II)-NO and Fe(II)-CO complexes undergo autophosphorylation and subsequently transfer the phosphat...
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| Publicado no: | Arch Biochem Biophys |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121028/ https://ncbi.nlm.nih.gov/pubmed/27729224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.10.005 |
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