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Transcription upregulation via force-induced direct stretching of chromatin

Mechanical forces play critical roles in the function of living cells. However, the underlying mechanisms of how forces influence nuclear events remain elusive. Here, we show that chromatin deformation as well as force-induced transcription of a green-fluorescent-protein (GFP) tagged bacterial-chrom...

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Dades bibliogràfiques
Publicat a:Nat Mater
Autors principals: Tajik, Arash, Zhang, Yuejin, Wei, Fuxiang, Sun, Jian, Jia, Qiong, Zhou, Wenwen, Singh, Rishi, Khanna, Nimish, Belmont, Andrew S., Wang, Ning
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121013/
https://ncbi.nlm.nih.gov/pubmed/27548707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4729
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