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Stress-induced EGFR trafficking: mechanisms, functions, and therapeutic implications
Epidermal growth factor receptor (EGFR) has fundamental roles in normal physiology and in cancer, making it a rational target for cancer therapy. Surprisingly, however, inhibitors that target canonical, ligand-stimulated EGFR signaling have proven to be largely ineffective in treating many EGFR-depe...
Shranjeno v:
| izdano v: | Trends Cell Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120732/ https://ncbi.nlm.nih.gov/pubmed/26827089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.12.006 |
| Oznake: |
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