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Phase I Trial of Weekly Topotecan and Gemcitabine in Patients With Solid Tumors
OBJECTIVE: This phase I trial was designed to determine the maximal tolerated dose (MTD) of the combination of topotecan and gemcitabine given in a weekly schedule. MATERIALS AND METHODS: In this single-arm, open label, dose-escalation study, we administered topotecan (0.75–1.5 mg/m(2)) and gemcitab...
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| Publicado en: | Am J Clin Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120668/ https://ncbi.nlm.nih.gov/pubmed/19194117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COC.0b013e318178e513 |
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