Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

Tumor-infiltrating regulatory T lymphocytes (Treg) can suppress effector T cells specific for tumor antigens. Deeper molecular definitions of tumor-infiltrating-lymphocytes could thus offer therapeutic opportunities. Transcriptomes of T helper 1 (Th1), Th17, and Treg cells infiltrating colorectal or...

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Published in:Immunity
Main Authors: De Simone, Marco, Arrigoni, Alberto, Rossetti, Grazisa, Gruarin, Paola, Ranzani, Valeria, Politano, Claudia, Bonnal, Raoul J.P., Provasi, Elena, Sarnicola, Maria Lucia, Panzeri, Ilaria, Moro, Monica, Crosti, Mariacristina, Mazzara, Saveria, Vaira, Valentina, Bosari, Silvano, Palleschi, Alessandro, Santambrogio, Luigi, Bovo, Giorgio, Zucchini, Nicola, Totis, Mauro, Gianotti, Luca, Cesana, Giancarlo, Perego, Roberto A., Maroni, Nirvana, Pisani Ceretti, Andrea, Opocher, Enrico, De Francesco, Raffaele, Geginat, Jens, Stunnenberg, Hendrik G., Abrignani, Sergio, Pagani, Massimiliano
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119953/
https://ncbi.nlm.nih.gov/pubmed/27851914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.021
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