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Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases

Phosphorylation at serine 235 (S235) of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) plays a critical role in the viral life cycle. For medical and virological interests, we exploited the HEK293T kidney cells to test 3 candidate protein kinases on NS5A S235 phosphorylation. Inhibitor...

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Publicat a:PLoS One
Autors principals: Lee, Kuan-Ying, Chen, Yi-Hung, Hsu, Shih-Chin, Yu, Ming-Jiun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119781/
https://ncbi.nlm.nih.gov/pubmed/27875595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166763
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